Angina is a condition that causes chest pain or discomfort due to reduced blood flow to the heart muscle. The cause of its occurrence is generally believed to be coronary atherosclerosis, which causes lumen stenosis and insufficient blood supply to the myocardium, resulting in an imbalance between myocardial supply and oxygen demand. Commonly used anti-angina APIs include nitrate ester and nitrite esters represented by nitroglycerin, calcium channel blockers (CCB) represented by nifedipine, and β-receptor blockers represented by propranolol, etc.